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An Illegal Drug Possibly Benefits For People With Multiple Sclerosis As Well As Some Ideas Involving The Idea
Known all over the world for its consciousness-altering characteristics, marijuana is reported to reduce involuntary muscle contractions experienced by some people with Multiple Sclerosis. Users of the renowned drug, that is derived from the flowering top of the hemp plant, cannabis sativa, have claimed that marijuana reportedly relieved some of their Multiple Sclerosis symptoms.
Reports that marijuana diminished Multiple Sclerosis involuntary muscle spasms resulted in a small number of clinical trials conducted to determine if a promising drug or other medical treatment may actually help people.
Initial clinical studies determined the function of tetrahydrocannabinol (THC), an active ingredient in marijuana, concerning the treatment of muscle spasms, tremor, and balance control in a restricted numbers of people afflicted with Multiple Sclerosis. However, the results of the studies are inconclusive, and clinical subjects reported an assortment of side effects.
However, the reports of the effect of THC to alleviate involuntary muscle spasms reveal contrasting results. Although some people reported feeling totally relaxed and also became less prone to involuntary muscle spasms, the observable fact cannot be specifically confirmed by objective testing. Results show that the analgesic effects of marijuana lasted a maximum of 3 hours and in increased doses corollary reactions of weakness, thirst, lightheadedness, short-term memory loss, space and time distortions, and lack of motor control have been reported.
In a study of THC concerning eight seriously disabled individuals with advanced tremor and lack of muscle coordination, 2 subjects reported considerable improvement with tremor, which was verified by a doctor's examination however 3 reported improvement that could not be verified. All eight subjects that were administered THC reported experiencing a high, whilst two reported sensations of uneasiness and restlessness.
A limited research on the effect of marijuana also revealed that the drug undermines motor coordination in posture control and equilibrium of people hurting from Multiple Sclerosis and even those who did not have Multiple Sclerosis, with all subjects reporting feelings of giddiness.
The National Academy of Science/Institute of Medicine issued a report on March 17, 1999 that the medicinal uses of marijuana raised additional questions. Although the report did conclude that smoking marijuana does not have a direct part in the treatment of Multiple Sclerosis, the possibility exists that specific compounds derived from marijuana might possibly alleviate some Multiple Sclerosis related symptoms, in particular those related to involuntary muscle spasms. The report recommends that scientific and controlled studies regarding the curative potential of cannabin compounds be undertaken combined with the safe development and dependable drug delivery tools.
Medical researchers have tested the capability of two derivatives from marijuana called cannabin and three synthetic cannabins to control unconscious muscle contractions and tremor, symptoms of the Multiple Sclerosis-like disease, in mice. These findings suggest that 4 different cannabins could temporarily relieve involuntary muscle spasms and/or tremor. Though the study recommended that derivatives of marijuana could be developed for human use, the primary obstacle would be to determine the right amount of these cannabins to make them a safe and workable treatment for those who have Multiple Sclerosis.
Using the results of studies conducted to date as a starting point, the National Multiple Sclerosis Society's Medical Advisory Board states there are presently insufficient conclusive data to warrant the recommendation of marijuana or its derivatives as a treatment for people afflicted with Multiple Sclerosis and that extended use may cause considerable serious side effects.
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